Can tumor profiling help kids beat cancer? new study aims to find out

NCT ID NCT02520713

Ongoing Knowledge-focused Sponsor: Dana-Farber Cancer Institute Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at whether testing the genes of a child's solid tumor can help doctors choose a more effective treatment. About 825 children and young adults with hard-to-treat solid tumors will have their tumors genetically profiled. The goal is to see if those who receive a treatment matched to their tumor's genetic changes live longer than those who do not.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Genetic testing and tumor profiling
What this could lead to: If successful, this could help doctors better match cancer treatments to a child's specific tumor genetics, potentially improving survival.
What could go wrong: This is an observational study, not a treatment trial. It may not prove that matching therapy improves outcomes, and many patients may not get a matching recommendation.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

childhood neoplasm neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PEDIATRIC SOLID TUMOR

Contacts and locations

Locations

Boston Children's Hospital

Boston, Massachusetts, 02215, United States
Children's Hospital Colorado

Aurora, Colorado, 80045, United States
Children's Hospital of Philadelphia

Philadelphia, Pennsylvania, 19104, United States
Children's National Medical Center

Washington D.C., District of Columbia, 20010, United States
Columbia University Medical Center

New York, New York, 10032, United States
Dana-Farber Cancer Institute

Boston, Massachusetts, 02215, United States
Nationwide Children's Hospital

Columbus, Ohio, 43205, United States
Seattle Children's Hospital

Seattle, Washington, 98105, United States
University of California San Francisco

San Francisco, California, 94158, United States
University of Chicago Comer Children's Hospital

Chicago, Illinois, 60637, United States
University of Texas Southwestern Medical Center at Dallas

Dallas, Texas, 75390, United States
University of Utah Childrens Medical Center

Salt Lake City, Utah, 84113, United States

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