Your own blood could help heal gum disease bone loss

NCT ID NCT07261878

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether adding a concentrate from the patient's own blood (injectable platelet rich fibrin, or I-PRF) to a standard bone graft helps repair bone defects caused by advanced gum disease. Twenty adults with stage III periodontitis and deep gum pockets will receive either the combination treatment or the graft alone during surgery. Researchers will measure bone fill and gum health at 3 and 6 months.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

injectable platelet rich fibrin (I-PRF) and xenograft

What this could lead to

If it works, this could offer a better way to repair bone damage from advanced gum disease using the patient's own blood.

What could go wrong

This is a very small early study with only 20 people, so results may not apply widely. The treatment is surgical and carries typical risks like infection or poor healing.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

chronic periodontitis periodontitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Faculty of Dental Medicine for Girls, Al- Azhar University

    Cairo, Cairo Governorate, Egypt

  • Ola Jamal

    Cairo, Cairo Governorate, Egypt