Your own blood could help heal gum disease bone loss

NCT ID NCT07261878

Ongoing Disease control Sponsor: Al-Azhar University Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether adding a concentrate from the patient's own blood (injectable platelet rich fibrin, or I-PRF) to a standard bone graft helps repair bone defects caused by advanced gum disease. Twenty adults with stage III periodontitis and deep gum pockets will receive either the combination treatment or the graft alone during surgery. Researchers will measure bone fill and gum health at 3 and 6 months.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: injectable platelet rich fibrin (I-PRF) and xenograft
What this could lead to: If it works, this could offer a better way to repair bone damage from advanced gum disease using the patient's own blood.
What could go wrong: This is a very small early study with only 20 people, so results may not apply widely. The treatment is surgical and carries typical risks like infection or poor healing.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

chronic periodontitis periodontitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

INTRABONY DEFECT INTRABONY DEFECTS IN CHRONIC PERIODONTITIS

Contacts and locations

Locations

Faculty of Dental Medicine for Girls, Al- Azhar University

Cairo, Cairo Governorate, Egypt
Ola Jamal

Cairo, Cairo Governorate, Egypt

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