Blood-Derived gel may speed healing after wisdom tooth removal

NCT ID NCT07257328

Completed Disease control Sponsor: Saglik Bilimleri Universitesi Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether applying a gel made from a patient's own blood (i-PRF) to the extraction site after wisdom tooth removal helps the socket heal better than standard surgery alone. Thirty-two healthy, non-smoking adults had both lower wisdom teeth removed, with one side receiving i-PRF and the other serving as a control. Healing was assessed using a special scale. The goal is to see if i-PRF can improve recovery after dental surgery.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: injectable platelet-rich fibrin (i-PRF)
What this could lead to: If i-PRF improves socket healing, it could become a standard addition to dental surgeries to speed recovery and reduce complications.
What could go wrong: This is a small, completed study with only 32 participants. Results may not apply to smokers, pregnant women, or those with health conditions. i-PRF may not significantly improve healing over standard care.

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Conditions

The condition(s) this trial relates to.

injury

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

TOOTH EXTRACTION SITE HEALING WOUND HEALING

Contacts and locations

Locations

University of Health Sciences

Istanbul, Turkey (Türkiye)

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