Could a virus trigger mental illness? new study investigates

NCT ID NCT02878408

Recruiting now Knowledge-focused Sponsor: Pr. Marion Leboyer Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study is collecting blood samples and questionnaires from 1,100 people with bipolar disorder or schizophrenia. Researchers are looking for links between genetics, inflammation, and a dormant virus called HERV-W. The goal is to find new biomarkers and pave the way for future treatments.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this research could identify new biomarkers and point toward treatments that target the HERV-W virus, potentially slowing or stopping psychosis progression.
What could go wrong: This is an observational study focused on understanding disease mechanisms, not testing a treatment. Any potential therapies are still in early preclinical stages and may not work in humans.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

bipolar disorder schizophrenia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BIPOLAR DISORDER SCHIZOPHRENIA

Contacts and locations

Locations

Clinical Investigations Center of Mondor Hospital
RECRUITING

Créteil, 94000, France
EPS Maison Blanche
RECRUITING

Paris, 75020, France
Psychiatry Department of Mondor Hospital
RECRUITING

Créteil, France, 94000, France
Psychiatry Department of Perrens Hospital
NOT_YET_RECRUITING

Bordeaux, France
Psychiatry Department of R. Dubos Hospital
RECRUITING

Pontoise, France
Psychiatry Department of Widal Hospital
RECRUITING

Paris, 75010, France

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