New hope for suicidal depression: online therapy plus ketamine shows promise in Rapid-Action trial

NCT ID NCT06480500

First seen Jan 02, 2026 · Last updated May 02, 2026 · Updated 17 times

Summary

This study tests whether adding intravenous ketamine to internet-based cognitive behavioural therapy (i-CBT) can quickly reduce suicidal thoughts and behaviors in people with treatment-resistant depression. About 110 adults will receive weekly i-CBT for 13 weeks, and half will also get six ketamine infusions over the first month. The goal is to see if the combination works faster and better than i-CBT alone.

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Contacts and locations

Study contacts

  • Contact

    Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Toronto General Hospital

    RECRUITING

    Toronto, Ontario, Canada

    Contact

    Contact Email: •••••@•••••

Conditions

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