Can a 3-Week radiation course beat 5 weeks for breast cancer patients with reconstruction?

NCT ID NCT07084519

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This phase 3 trial tests whether a shorter, higher-dose radiation schedule (3 weeks) is as safe and effective as the standard 5-week schedule for women with high-risk breast cancer who have had a mastectomy and immediate implant reconstruction. The study will enroll 506 women and track reconstruction failure, side effects, and cancer recurrence. The goal is to see if the shorter course can reduce treatment time without increasing complications.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

radiation therapy (hypofractionated or conventional)

What this could lead to

If successful, a shorter 3-week radiation course could become the new standard, reducing treatment burden and possibly lowering complication rates for women with breast reconstruction.

What could go wrong

This is still a recruiting phase 3 trial; results may show no benefit or higher reconstruction failure with the shorter regimen. Individual outcomes vary.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

breast adenocarcinoma breast cancer breast neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Department of Radiation Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College

    RECRUITING

    Beijing, Province, 10000, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••