Could 3 radiation sessions be enough for prostate cancer?

NCT ID NCT06914544

Recruiting now Disease control Sponsor: University Hospital Schleswig-Holstein Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study is testing a new, shorter radiation treatment for men with early-stage prostate cancer. Instead of the usual 5 sessions, doctors will give 3 high-dose radiation treatments. The goal is to see if this approach is safe and causes fewer side effects while still controlling the cancer. About 175 men will take part, and researchers will track side effects and quality of life for one year.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: radiation therapy (hypofractionated radiosurgery)
What this could lead to: If successful, this could offer a more convenient and less toxic radiation option for men with localized prostate cancer, reducing treatment from 5 sessions to 3.
What could go wrong: This is a mid-stage trial with only 175 participants, so results may not apply to everyone. There is still a risk of urinary or bowel side effects, and the treatment may not control the cancer as well as standard approaches.

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Conditions

The condition(s) this trial relates to.

prostate cancer prostate carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PROSTATE CANCER

Contacts and locations

Locations

CyberKnife Centrum Mitteldeutschland
RECRUITING

Erfurt, Thuringia, 99089, Germany
European Radiosurgery Center Munich
RECRUITING

Munich, Hesse, 81377, Germany
Saphir Radiosurgery Center Frankfurt am Main
RECRUITING

Frankfurt am Main, Hesse, 60528, Germany
Saphir Radiosurgery Center Norther Germany
ACTIVE_NOT_RECRUITING

Kiel, Schleswig-Holstein, 24105, Germany
University Hospital Frankfurt
SUSPENDED

Frankfurt am Main, Hesse, 60528, Germany
University Medical Center Schleswig-Holstein
RECRUITING

Kiel, Schleswig-Holstein, 24105, Germany

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