Fewer radiation sessions before sarcoma surgery shows promise in early trial
NCT ID NCT02634710
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This pilot study tested a shorter course of radiation (hypofractionated) given before surgery for soft tissue sarcoma of the arm, leg, or chest wall. The goal was to see if this approach is safe, feasible, and controls the tumor locally. Thirty-five adults with localized sarcoma completed the treatment, and researchers measured recurrence and side effects.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Hypofractionated radiation therapy
- What this could lead to
- If successful, this shorter radiation schedule could become a standard option before surgery for soft tissue sarcoma, reducing treatment time while maintaining tumor control.
- What could go wrong
- This is a small pilot study with only 35 participants and no comparison group. The results may not apply to all sarcoma types or locations, and the higher daily radiation dose could increase side effects.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
-
Froedtert Hospital
Milwaukee, Wisconsin, 53226, United States
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