Oxygen therapy could tame severe colitis Flare-Ups
NCT ID NCT07257588
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether adding hyperbaric oxygen therapy (breathing pure oxygen in a pressurized chamber) to standard steroid drugs helps people with severe ulcerative colitis get better faster. About 44 adults with acute severe colitis will be randomly assigned to receive either standard treatment alone or standard treatment plus hyperbaric oxygen. The goal is to see if the oxygen therapy improves symptoms and reduces inflammation in the colon.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
hyperbaric oxygen therapy
What this could lead to
If it works, this could provide a new, non-drug option to help control severe flare-ups of ulcerative colitis.
What could go wrong
This is a small, early-stage study with only 44 participants, so results may not apply to everyone. Hyperbaric oxygen can cause ear or sinus discomfort in some people.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Xijing hospital of digestive diseases
Xi'an, Shaanxi, 710032, China