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CO poisoning treatment study cut short after only two patients

NCT ID NCT06619717

Knowledge-focused Sponsor: University of Alberta Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early This study
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study aimed to find out whether one or three sessions of hyperbaric oxygen therapy works better to prevent long-term brain damage after carbon monoxide poisoning. Researchers planned to enroll adults with acute poisoning and test their memory, attention, and other thinking skills. However, the study was terminated early after enrolling only 2 participants, so no meaningful conclusions can be drawn.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Hyperbaric oxygen therapy (breathing pure oxygen in a pressurized chamber)
What this could lead to
If successful, this could clarify whether one or three hyperbaric treatments is better for preventing long-term brain problems after carbon monoxide poisoning.
What could go wrong
The study was terminated early with only 2 participants, so it cannot provide reliable answers. Results may not apply to all patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

2 people

The number who actually took part.

Started

Jan 2025

Finished

Feb 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

17 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * All adult (over 17 years old) patients referred to a Hyperbaric Unit for acute carbon monoxide poisoning. Exclusion Criteria: * Obtunded * Mechanically ventilated * Pregnant * Incarcerated * Cognitively impaired (acutely or chronically)

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Conditions

The condition(s) this trial relates to.

carbon monoxide poisoning

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Carbon monoxide poisoning Hyperbaric oxygen therapy

Contacts and locations

Locations

  • University of Alberta

    Edmonton, Alberta, T6G2R3, Canada

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