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Can oxygen therapy help fat grafts survive better in breast reconstruction?

NCT ID NCT07140198

Recruiting now Disease control Sponsor: University Hospital, Geneva Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether hyperbaric oxygen therapy (HBOT) can help transplanted fat survive longer in breast reconstruction after radiation treatment. Sixteen women who had radiation for breast cancer will each receive two fat grafting sessions—one with HBOT and one without—in a random order. MRI scans will measure how much fat remains after six months.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
hyperbaric oxygen therapy (HBOT)
What this could lead to
If it works, this could improve the success of fat grafting for breast reconstruction after radiation, leading to better cosmetic outcomes.
What could go wrong
This is a very small early-phase trial with only 16 patients, so results may not apply widely. HBOT also carries risks like ear or sinus pain and, rarely, lung injury.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

breast cancer

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BREAST RECONSTRUCTION HYPERBARIC OXYGEN THERAPY LIPOFILLING

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Geneva University Hospitals

    RECRUITING

    Geneva, Canton of Geneva, 1206, Switzerland

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

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