Can a malaria drug help kids with rare lung disease?
NCT ID NCT04532346
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether hydroxychloroquine, a drug used for malaria and arthritis, can safely improve breathing in children with interstitial lung disease caused by genetic mutations. Researchers will enroll 60 children and randomly assign them to receive the drug or not, measuring oxygen levels and breathing rates. The goal is to see if the drug reduces symptoms like coughing and breathing difficulty.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
hydroxychloroquine
What this could lead to
If it works, this could point toward a treatment to improve breathing and reduce symptoms in children with genetic lung disease.
What could go wrong
This is a very early, small trial (60 children) with no guarantee of success. Hydroxychloroquine may not work for these rare conditions and could have side effects.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Children's hospital of Fudan University
RECRUITINGShanghai, Shanghai Municipality, 201102, China
Contact Phone: •••-•••-•••• Email: •••••@•••••