Cheap steroid could save lives from hospital lung infections

NCT ID NCT05354778

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether the steroid hydrocortisone, added to usual care, can help ICU patients with severe hospital-acquired pneumonia. Researchers will compare hydrocortisone against a placebo in 180 adults. The goal is to see if the drug reduces early death or worsening of breathing and heart function.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Hydrocortisone (a corticosteroid)

What this could lead to

If it works, this could provide a cheap, widely available treatment to reduce deaths from hospital-acquired pneumonia in intensive care.

What could go wrong

This is an early-stage trial with only 180 patients, so results may not apply to everyone. Corticosteroids also carry risks like infection or blood sugar problems.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Healthcare-Associated Pneumonia nosocomial infection pneumonia Pneumonia, Ventilator-Associated

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Hospital do Servidor Publico Estadual

    RECRUITING

    São Paulo, Sao Paulo SP, 04039-901, Brazil

    Contact Phone: •••-•••-•••• Email: •••••@•••••