Steroid withdrawal relief: new study tests hydrocortisone for lingering fatigue

NCT ID NCT05193396

First seen Nov 01, 2025 · Last updated May 07, 2026 · Updated 27 times

Summary

This study tests whether a low-dose hydrocortisone pill can relieve symptoms like fatigue and dizziness in people who have stopped taking steroids for giant cell arteritis or polymyalgia rheumatica. About 100 adults aged 50 and older who have been off steroids for 2 to 12 weeks will receive either hydrocortisone or a placebo for 16 weeks. The goal is to see if this treatment improves quality of life and reduces symptoms of adrenal insufficiency.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Department of Endocrinology and Internal Medicine, Aarhus University Hospital

    RECRUITING

    Aarhus, Denmark

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Department of Endocrinology, Odense University Hospital

    RECRUITING

    Odense, 5230, Denmark

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Department of Nephrology and Endocrinology, Rigshospitalet

    RECRUITING

    Copenhagen, Denmark

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.