Could a dental exam help spot a rare neurological disease?
NCT ID NCT07799233
First seen Sep 02, 2026 · Last updated Sep 03, 2026 · Updated 1 time
Summary
Researchers at the University of Barcelona are comparing the teeth, jaws, and facial structure of 25 people with hereditary spastic paraplegia (HSP) against 25 people without the condition. They use non-invasive scans and X-rays to measure jaw relationships, tooth alignment, and other features. The goal is to see whether HSP produces a recognizable pattern in the mouth and face that could aid in diagnosis and dental care.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If a distinct dental and facial pattern exists in HSP, it could help dentists and doctors recognize the condition earlier and guide dental care.
- What could go wrong
- This is a small, early observational study, so any patterns found may not apply to all people with HSP. It only looks for links, not causes.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
-
50 people
The number who actually took part.
- Started
-
Oct 2025
- Finished
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Apr 2026
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Members of the Catalan branch of the Spanish Hereditary Spastic Paraplegia Association.
- Ages
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Children (under 18), adults (18 to 64) and older adults (65 and over)
- Sex
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Anyone
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Confirmed diagnosis of HSP. * Caucasian ethnicity. Exclusion Criteria: * Patients with HSP who have undergone orthognathic surgery or orthodontic, orthopedic, or functional treatment.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Hospital Odontològic de la Universitat de Barcelona
L'Hospitalet de Llobregat, Barcelona, 08907, Spain
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