Could a dental exam help spot a rare neurological disease?

NCT ID NCT07799233

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

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Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Sep 02, 2026 · Last updated Sep 03, 2026 · Updated 1 time

Summary

Researchers at the University of Barcelona are comparing the teeth, jaws, and facial structure of 25 people with hereditary spastic paraplegia (HSP) against 25 people without the condition. They use non-invasive scans and X-rays to measure jaw relationships, tooth alignment, and other features. The goal is to see whether HSP produces a recognizable pattern in the mouth and face that could aid in diagnosis and dental care.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If a distinct dental and facial pattern exists in HSP, it could help dentists and doctors recognize the condition earlier and guide dental care.
What could go wrong
This is a small, early observational study, so any patterns found may not apply to all people with HSP. It only looks for links, not causes.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

50 people

The number who actually took part.

Started

Oct 2025

Finished

Apr 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Members of the Catalan branch of the Spanish Hereditary Spastic Paraplegia Association.

Ages

Children (under 18), adults (18 to 64) and older adults (65 and over)

Sex

Anyone

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Confirmed diagnosis of HSP. * Caucasian ethnicity. Exclusion Criteria: * Patients with HSP who have undergone orthognathic surgery or orthodontic, orthopedic, or functional treatment.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Hospital Odontològic de la Universitat de Barcelona

    L'Hospitalet de Llobregat, Barcelona, 08907, Spain

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