Simple blood test could spot throat Cancer's return early
NCT ID NCT05582122
First seen Jun 24, 2026 · Last updated Jun 26, 2026 · Updated 1 time
Summary
This study tests whether a blood test that looks for HPV DNA can help monitor patients treated for HPV-related oropharyngeal cancer. The goal is to see if the test can detect cancer recurrence earlier than standard methods, and also reduce the number of routine follow-up visits for patients with negative results. About 420 adults who have completed curative treatment will be followed for up to 5 years.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
HPV16 circulating DNA test (ddPCR blood test)
What this could lead to
If successful, this blood test could help doctors catch cancer recurrence earlier and reduce the number of follow-up visits for many patients.
What could go wrong
This is a phase 2 trial, so the test may not prove accurate enough for routine use. It only applies to HPV16-positive oropharyngeal cancers, not all throat cancers.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Antoine Lacassagne - NICE
ACTIVE_NOT_RECRUITINGNice, France
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CHU De Nîmes ICG
ACTIVE_NOT_RECRUITINGNîmes, France
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Clinique St Vincent- Réunion
ACTIVE_NOT_RECRUITINGSaint-Denis, La Réunion, France
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Eugène Marquis-Rennes
RECRUITINGRennes, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Georges-François Leclerc
RECRUITINGDijon, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Gustave Roussy
RECRUITINGVillejuif, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Hôpital Européen Georges Pompidou
RECRUITINGParis, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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ICANS Strasbourg
RECRUITINGStrasbourg, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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ICO - Site St Herblain
NOT_YET_RECRUITINGSaint-Herblain, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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ISC Avignon
RECRUITINGAvignon, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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IUCT Oncopole Toulouse
RECRUITINGToulouse, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Institut Curie - Paris
NOT_YET_RECRUITINGParis, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Institut de cancérologie de Lorraine
RECRUITINGVandœuvre-lès-Nancy, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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La Timone-AP-HM Marseille
RECRUITINGMarseille, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Oscar Lambret- Lille
NOT_YET_RECRUITINGLille, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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TENON - APHP Paris
RECRUITINGParis, France
Contact Phone: •••-•••-•••• Email: •••••@•••••