Could a salad ingredient help treat diabetes? new trial underway
NCT ID NCT07546929
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This Phase 2 trial tests HP-211, a botanical extract from common vegetables like endive and lettuce, in 300 people with type 2 diabetes. The goal is to see if it can improve how the body uses insulin and lower blood sugar levels over 90 days. Participants take HP-211 or a placebo twice daily, and researchers measure changes in HbA1c, a key blood sugar marker.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- HP-211 (a botanical extract from endive, lettuce, and tarragon)
- What this could lead to
- If it works, HP-211 could offer a new, natural option to help control blood sugar and reduce insulin resistance in type 2 diabetes, potentially preventing or delaying complications.
- What could go wrong
- This is an early Phase 2 study with only 300 people, so results may not apply to everyone. The extract is new, and its long-term safety and effectiveness are not yet proven.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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AMR Clinical - El Dorado
RECRUITINGEl Dorado, Kansas, 67042, United States
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Advanced Medical Research
RECRUITINGMaumee, Ohio, 43537, United States
Contact Email: •••••@•••••
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Alliance Clinical Canoga Park (Hope Clinical Research)
RECRUITINGCanoga Park, California, 91303, United States
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Alliance Clinical Las Vegas (Excel Clinical Research)
RECRUITINGLas Vegas, Nevada, 89109, United States
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Alliance Clinical Lewisville (Epic Clinical Research)
RECRUITINGLewisville, Texas, 75057, United States
Contact Email: •••••@•••••
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Arcturus Healthcare, PLC, Troy Internal Medicine Research Division
RECRUITINGTroy, Michigan, 48098, United States
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Avantis Clinical Research
RECRUITINGMiami, Florida, 33155, United States
Contact Email: •••••@•••••
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Burke Internal Medicine & Research
RECRUITINGBurke, Virginia, 22015, United States
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David Kavtaradze MD InC
RECRUITINGCordele, Georgia, 31015, United States
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Diabetes & Endocrinology Associates of Stark County, Inc.
RECRUITINGCanton, Ohio, 44718, United States
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IMIC Research
RECRUITINGMiami, Florida, 33176, United States
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Simcare Medical Research, LLC.
RECRUITINGSugar Land, Texas, 77478, United States
Contact Email: •••••@•••••
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South Broward Research
RECRUITINGMiramar, Florida, 33027, United States
Contact Email: •••••@•••••
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Southwest General Healthcare Center
RECRUITINGFort Myers, Florida, 33907, United States
Contact Email: •••••@•••••
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Tandem Clinical Research (Interspond)
RECRUITINGMarrero, Louisiana, 70072, United States
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Tekton Research
RECRUITINGIrving, Texas, 75039, United States
Contact Email: •••••@•••••
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Tekton Research
RECRUITINGMcKinney, Texas, 75069, United States
Contact Email: •••••@•••••
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Tekton Research
RECRUITINGSan Antonio, Texas, 78258, United States
Contact Email: •••••@•••••
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Tekton Research
RECRUITINGMidlothian, Virginia, 23112, United States
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Universal Axon Clinical Research
RECRUITINGDoral, Florida, 33166, United States
Contact Email: •••••@•••••
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Velocity Clinical Research Dallas
RECRUITINGDallas, Texas, 75230, United States
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Velocity Clinical Research New Smyrna Beach
RECRUITINGEdgewater, Florida, 32132, United States
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Velocity Clinical Research Norfolk
RECRUITINGNorfolk, Nebraska, 68701, United States
Contact Email: •••••@•••••
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Velocity Clinical Research Providence
RECRUITINGEast Greenwich, Rhode Island, 02818, United States
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Velocity Clinical Research Waco
RECRUITINGWaco, Texas, 76710, United States
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