Could a salad ingredient help treat diabetes? new trial underway
NCT ID NCT07546929
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This Phase 2 trial tests HP-211, a botanical extract from common vegetables like endive and lettuce, in 300 people with type 2 diabetes. The goal is to see if it can improve how the body uses insulin and lower blood sugar levels over 90 days. Participants take HP-211 or a placebo twice daily, and researchers measure changes in HbA1c, a key blood sugar marker.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
HP-211 (a botanical extract from endive, lettuce, and tarragon)
What this could lead to
If it works, HP-211 could offer a new, natural option to help control blood sugar and reduce insulin resistance in type 2 diabetes, potentially preventing or delaying complications.
What could go wrong
This is an early Phase 2 study with only 300 people, so results may not apply to everyone. The extract is new, and its long-term safety and effectiveness are not yet proven.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
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AMR Clinical - El Dorado
RECRUITINGEl Dorado, Kansas, 67042, United States
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Advanced Medical Research
RECRUITINGMaumee, Ohio, 43537, United States
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Alliance Clinical Canoga Park (Hope Clinical Research)
RECRUITINGCanoga Park, California, 91303, United States
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Alliance Clinical Las Vegas (Excel Clinical Research)
RECRUITINGLas Vegas, Nevada, 89109, United States
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Alliance Clinical Lewisville (Epic Clinical Research)
RECRUITINGLewisville, Texas, 75057, United States
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Arcturus Healthcare, PLC, Troy Internal Medicine Research Division
RECRUITINGTroy, Michigan, 48098, United States
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Avantis Clinical Research
RECRUITINGMiami, Florida, 33155, United States
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Burke Internal Medicine & Research
RECRUITINGBurke, Virginia, 22015, United States
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David Kavtaradze MD InC
RECRUITINGCordele, Georgia, 31015, United States
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Diabetes & Endocrinology Associates of Stark County, Inc.
RECRUITINGCanton, Ohio, 44718, United States
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IMIC Research
RECRUITINGMiami, Florida, 33176, United States
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Simcare Medical Research, LLC.
RECRUITINGSugar Land, Texas, 77478, United States
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South Broward Research
RECRUITINGMiramar, Florida, 33027, United States
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Southwest General Healthcare Center
RECRUITINGFort Myers, Florida, 33907, United States
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Tandem Clinical Research (Interspond)
RECRUITINGMarrero, Louisiana, 70072, United States
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Tekton Research
RECRUITINGIrving, Texas, 75039, United States
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Tekton Research
RECRUITINGMcKinney, Texas, 75069, United States
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Tekton Research
RECRUITINGSan Antonio, Texas, 78258, United States
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Tekton Research
RECRUITINGMidlothian, Virginia, 23112, United States
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Universal Axon Clinical Research
RECRUITINGDoral, Florida, 33166, United States
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Velocity Clinical Research Dallas
RECRUITINGDallas, Texas, 75230, United States
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Velocity Clinical Research New Smyrna Beach
RECRUITINGEdgewater, Florida, 32132, United States
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Velocity Clinical Research Norfolk
RECRUITINGNorfolk, Nebraska, 68701, United States
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Velocity Clinical Research Providence
RECRUITINGEast Greenwich, Rhode Island, 02818, United States
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Velocity Clinical Research Waco
RECRUITINGWaco, Texas, 76710, United States
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