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Can strength training rewire the brain?

NCT ID NCT06413199

Knowledge-focused Sponsor: Pakistan Society for Rehabilitation of Differently Abled Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Sep 01, 2026 · Last updated Sep 02, 2026 · Updated 1 time

Summary

This trial tests whether a two-month resistance training program alters brain and nerve activity in healthy adults. Researchers will measure nerve speed, brain waves, muscle strength, and blood protein levels before and after training. The goal is to understand how the nervous system adapts to strength exercise.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Resistance training (weight lifting) program
What this could lead to
If it works, this could reveal how strength training shapes the nervous system, possibly informing exercise-based therapies for brain health.
What could go wrong
This is an early, small study in healthy people, so results may not apply to broader populations or lead to direct treatments.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

104 people

The number who actually took part.

Started

Aug 2023

Finished

Sep 2024

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 35 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Body Mass Index should be 18.5-24.9 kg/m2. * Participants were untrained and had not engaged in resistance exercise within 6 months prior to beginning the study. Exclusion Criteria: * Participants with any kind of Gastrointestinal Tract disturbance will be excluded from the study. * Participants with any kind of Musculoskeletal injury will be excluded from the study. * Participant with any kind of Neurological disturbance will be excluded from the study. * Participants who use tobacco products within the previous 6 months. * Participants who take any type of medication within the previous 6 months.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Resistance training

Contacts and locations

Locations

  • PSRD Hospital

    Lahore, Punjab Province, 54000, Pakistan

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