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Could a supplement that mimics human muscle boost strength and speed recovery?

NCT ID NCT07715201

Symptom relief Sponsor: Orivian inc Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 20, 2026 · Last updated Jul 24, 2026 · Updated 3 times

Summary

This study tests a dietary supplement called HME (Human Muscle Equivalent), which contains amino acids that match the composition of human skeletal muscle. Fifty trained adult males—competitive athletes or certified fitness professionals—will take either HME or a placebo daily for 10 weeks, including 8 weeks of supervised resistance training. The main goal is to see if HME improves overall strength more than placebo, with additional measures of jump height, muscle soreness, and recovery.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
a two-component amino acid formulation (free-form amino acid powder matched to human skeletal muscle profile plus slow-release beta-alanine capsule)
What this could lead to
If it works, this supplement could help athletes and fitness professionals improve strength and recovery more effectively than standard protein or amino acid supplements.
What could go wrong
This is a small pilot study with only 50 participants, so results may not be generalizable. The supplement may show no benefit over placebo, and individual responses can vary.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 50 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jun 2026

Expected to finish

Mar 2027

An estimate. End dates often move.

Lead sponsor

A company

The lead sponsor is a pharmaceutical, biotech, or medical-device company.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 45 years

Sex

Male participants only

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age 18 to 45 years inclusive * Biological male * Active competitive athlete in a recognized sport OR certified fitness professional (personal trainer, strength and conditioning coach, or equivalent) * Minimum 3 structured resistance-training sessions per week for at least 1 year continuously * Habitual protein intake 1.2 to 2.0 g/kg/day confirmed by 7-day food diary at screening * Current creatine users willing to use study-provided creatine monohydrate 5 g/day; non-users willing not to initiate creatine during the trial * Able to provide written informed consent in English * Willing and able to attend all supervised training sessions and assessment visits for 10 weeks * Access to a digital kitchen scale or willing to obtain one for food-record completion Exclusion Criteria: * Use of anabolic steroids, SARMs, prohormones, or beta-alanine supplements (other than the study product) within 8 weeks of screening * Current use of any amino acid supplement or weight-gainer product not cleared by the research coordinator * Currently in an active competitive season with non-negotiable training demands the investigator determines are incompatible with the supervised programme * Musculoskeletal injury in the preceding 3 months affecting ability to perform study assessments or training * Any medical condition, medication, or dietary restriction that in the Medical Officer's opinion would affect the safety or validity of participation * Participation in another intervention study within 4 weeks of screening * Unwillingness to standardize creatine intake per protocol (current users) or to abstain from initiating creatine (non-users)

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Athletic performance Muscle strength Resistance training

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

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Contacts and locations

Locations

  • The Institute of Human Mechanics/ JUNXION Performance

    RECRUITING

    Toronto, Ontario, M8Z 2R4, Canada

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