Hormone boost may shield soldiers from training injuries
NCT ID NCT06455969
First seen Aug 18, 2026 · Last updated Aug 18, 2026
Summary
This trial tests whether altering sex hormone levels can make muscles, tendons, and bones more resilient to the physical and mental stress of military-style training. Healthy adults aged 18-40 will undergo a 4-week training program, with some receiving goserelin to suppress hormones and others also getting testosterone replacement. Researchers will measure changes in tissue structure, body composition, and performance to see if this hormonal approach could prevent common training injuries.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- goserelin (Zoladex) and testosterone gel (AndroGel)
- What this could lead to
- If successful, this could lead to new ways to protect military personnel from training-related injuries, improving readiness and reducing medical costs.
- What could go wrong
- This is a Phase 4 trial with 120 participants, so results may not apply broadly. Hormonal interventions can have side effects, and the study's specific setting may limit generalizability.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Neuromuscular Research Laboratory
RECRUITINGPittsburgh, Pennsylvania, 15203, United States
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