Could a headset at home lift depression when pills fail?

NCT ID NCT05930509

Completed Symptom relief Sponsor: Institut Guttmann Source: ClinicalTrials.gov ↗

First seen Jul 02, 2026 · Last updated Jul 02, 2026

Summary

This study tests whether a non-invasive brain stimulation device, used at home, can safely and effectively ease symptoms of major depression in people who have not improved with medication. Participants use the device for 30 minutes a day, five days a week, for four weeks. The trial measures how well people stick with the treatment, any side effects, and changes in depression scores.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: transcranial direct current stimulation (tDCS) device
What this could lead to: If it works, this could offer a convenient, at-home treatment option for people with depression that hasn't responded to medication.
What could go wrong: This is a small, early-stage study focused on feasibility and safety, so results may not confirm effectiveness. The treatment requires daily sessions and help from a live-in adult.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

major depressive disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

MAJOR DEPRESSIVE DISORDER

Contacts and locations

Locations

Guttmann Barcelona

Barcelona, Barcelona, 08027, Spain

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