Could a headset at home lift depression when pills fail?
NCT ID NCT05930509
First seen Jul 02, 2026 · Last updated Jul 02, 2026
Summary
This study tests whether a non-invasive brain stimulation device, used at home, can safely and effectively ease symptoms of major depression in people who have not improved with medication. Participants use the device for 30 minutes a day, five days a week, for four weeks. The trial measures how well people stick with the treatment, any side effects, and changes in depression scores.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
transcranial direct current stimulation (tDCS) device
What this could lead to
If it works, this could offer a convenient, at-home treatment option for people with depression that hasn't responded to medication.
What could go wrong
This is a small, early-stage study focused on feasibility and safety, so results may not confirm effectiveness. The treatment requires daily sessions and help from a live-in adult.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- NIR-TLT for Major Depressive Disorder - NCT05435820
- Ketamine Biomarkers for Depression Trial - NCT03573349
- Home-Based Light Therapy for Depression Trial (NCT07111390)
- Home-Based tDCS for Depression in MS – NCT06901687
- Whole-Body Hyperthermia for Mood & Anxiety Disor NCT06144294
- Deep Brain Stimulation for Depression Trial NCT00367003
Contacts and locations
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Locations
-
Guttmann Barcelona
Barcelona, Barcelona, 08027, Spain