Gene-Edited stem cells aim to tame HIV

NCT ID NCT02500849

Ongoing Disease control Sponsor: City of Hope Medical Center Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether giving HIV patients their own genetically modified stem cells is safe and feasible. The cells are changed to resist HIV, and patients receive a mild chemotherapy drug before infusion. The goal is to see if the modified cells can help control the virus, but this is an early safety trial with only 12 participants.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

AIDS HIV infectious disease immune system disorder inborn error of immunity RNA Virus Infections sexually transmitted disease uterine carcinosarcoma viral infectious disease viral sexually transmitted disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HIV

Contacts and locations

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Locations

Circle CARE Center, LLC

Norwalk, Connecticut, 06850, United States
City of Hope Medical Center

Duarte, California, 91010, United States
Mills Clinical Research

Los Angeles, California, 90069, United States
Quest Clinical Research

San Francisco, California, 94115, United States
UCLA CARE Center

Los Angeles, California, 90035, United States