HIV and fatty liver: scientists hunt for hidden clues in the blood

NCT ID NCT07640880

Not yet recruiting Knowledge-focused Sponsor: Yinzhong Shen Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at how HIV might change the way the body handles fats in the liver, leading to fatty liver disease. Researchers will collect one blood sample from 120 adults: people with HIV and fatty liver, people without HIV but with fatty liver, and healthy controls. By analyzing fats, proteins, and genetic material in the blood, they hope to find unique markers that could lead to better diagnosis for fatty liver in people with HIV.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this study could reveal how HIV changes fat metabolism in the liver and lead to better, non-invasive blood tests for fatty liver disease in people with HIV.
What could go wrong: This is an early observational study, not a treatment trial. It only looks at blood samples at one time point, so it cannot prove cause and effect or lead directly to a new therapy.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

AIDS HIV infectious disease metabolic dysfunction-associated steatotic liver disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HIV (HUMAN IMMUNODEFICIENCY VIRUS) MASLD

Contacts and locations

Locations

Shanghai Public Health Clinical Center

Shanghai, Shanghai Municipality, 201508, China

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