Can talking about stigma help people with HIV and depression?

NCT ID NCT06951542

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This pilot study in Malawi tests whether adding stigma-reduction counseling to standard depression treatment helps people living with HIV. Two hundred adults with HIV and depressive symptoms will receive counseling sessions that challenge myths and build coping skills. Researchers will measure if the approach is acceptable, feasible, and shows early signs of improving depression and HIV care engagement.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Stigma Reduction Counseling

What this could lead to

If it works, this could point toward a practical way to improve mental health and HIV care engagement by addressing stigma.

What could go wrong

This is a small pilot trial focused on feasibility, not proof of effectiveness. Results may not apply to other settings.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Depression HIV infectious disease major depressive disorder Social Stigma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Mulanje District Hospital

    Mulanje, Malawi

  • Salima District Hospital

    Salima, Malawi