Sound waves zapping liver tumors? new device tested in 24 patients
NCT ID NCT04573881
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This trial tests a device called HistoSonics that uses focused ultrasound (sound waves) to mechanically destroy liver tumors without heat or needles. It includes 24 adults with liver cancer or tumors that spread to the liver. The main goals are to see if the device can fully cover the tumor and to check for serious side effects within 30 days.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Histotripsy (focused ultrasound device)
What this could lead to
If successful, this could offer a non-invasive, needle-free option to destroy liver tumors without surgery or radiation.
What could go wrong
This is a very early, small study (24 people) with no control group. It only checks if the device can cover the tumor and if major complications occur within 30 days. Long-term benefits or risks are unknown.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Istituto Clinico Humanitas - Humanitas Mirasole S.P.A.
Milan, Italy
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Leeds Teaching Hospitals NHS Trust
Leeds, LS9 7TF, United Kingdom
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Städtisches Klinikum Braunschweig gGmbH
Braunschweig, Germany
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The Newcastle Upon Tyne Hospitals NHS Foundation Trust
Newcastle, NE7 7DN, United Kingdom
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Universitätsklinikum Magdeburg Klinik für Radiologie und Nuklearmedizin
Magdeburg, 39120, Germany
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Vall d'Hebron
Barcelona, Spain