Scientists investigate Histidine's role in boosting immunotherapy for colorectal cancer

NCT ID NCT07586293

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This observational study looks at how histidine, a common amino acid, and its transporter SLC15A3 influence colorectal cancer's sensitivity to immunotherapy. Researchers will analyze tumor tissue and blood samples from 150 patients to understand why some cancers resist treatment. The goal is to find new targets that could improve immunotherapy effectiveness.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this study could point toward new ways to make colorectal cancer more responsive to immunotherapy.

What could go wrong

This is an observational study, not a treatment trial, so it won't directly test any new therapy. Results may not lead to immediate clinical changes.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

colorectal cancer colorectal neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

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  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••