Scientists investigate Histidine's role in boosting immunotherapy for colorectal cancer

NCT ID NCT07586293

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This observational study looks at how histidine, a common amino acid, and its transporter SLC15A3 influence colorectal cancer's sensitivity to immunotherapy. Researchers will analyze tumor tissue and blood samples from 150 patients to understand why some cancers resist treatment. The goal is to find new targets that could improve immunotherapy effectiveness.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to
If successful, this study could point toward new ways to make colorectal cancer more responsive to immunotherapy.
What could go wrong
This is an observational study, not a treatment trial, so it won't directly test any new therapy. Results may not lead to immediate clinical changes.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

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