Cure My Disease

Don't miss your cure!

 Log in / Sign up

Oxygen dilemma: which level saves preterm brains?

NCT ID NCT03825835

Recruiting now Disease control Sponsor: University of Alberta Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study compares using 30% versus 60% oxygen when resuscitating extremely preterm babies (born before 29 weeks). The goal is to see which oxygen level leads to better survival and fewer long-term developmental problems like cerebral palsy or vision/hearing loss. About 1,200 babies across multiple hospitals will take part, with each hospital switching between the two oxygen levels over time.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
oxygen
What this could lead to
If it works, this could establish the safest oxygen level to use when resuscitating extremely preterm babies, potentially reducing death and long-term brain injury.
What could go wrong
This is a large trial but still testing a common practice; the difference between 30% and 60% oxygen may be small, and results may not apply to all hospitals or babies.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for NEURODEVELOPMENTAL OUTCOME are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

Premature Birth respiratory distress syndrome in premature infants

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

NEURODEVELOPMENTAL OUTCOME PREMATURE INFANT RESPIRATORY DISTRESS SYNDROME IN PREMATURE INFANT

Contacts and locations

Locations

  • BC Children

    RECRUITING

    Vancouver, British Colubia, Canada

  • CHEO

    ACTIVE_NOT_RECRUITING

    Ottawa, Ontario, Canada

  • Chu University Laval

    RECRUITING

    Québec, Quebec, Canada

  • Foothills Hospital

    ACTIVE_NOT_RECRUITING

    Calgary, Alberta, Canada

  • Health Sciences

    RECRUITING

    Winnipeg, Manitoba, Canada

  • Hospital Germans Tries i Pujol

    WITHDRAWN

    Barcelona, Spain

  • Hospital Las Palmas

    WITHDRAWN

    Las Palmas de Gran Canaria, Spain

  • Hospital Universitario Dexeus

    WITHDRAWN

    Barcelona, Spain

  • Hospital Universitario Materno Infantil Miguel Servet

    WITHDRAWN

    Zaragoza, Spain

  • Hospital de Asturias

    WITHDRAWN

    Oviedo, Spain

  • Hospital de la Arrixaca

    WITHDRAWN

    El Palmar, Spain

  • Janeway Children's Health and Rehabilitation Centre

    ACTIVE_NOT_RECRUITING

    St. John's, Newfoundland and Labrador, A1B 3V6, Canada

  • McGill Univeristy

    ACTIVE_NOT_RECRUITING

    Montreal, Quebec, Canada

  • Neonatal Intensive Care Unit - Hamilton Health Sciences

    ACTIVE_NOT_RECRUITING

    Hamilton, Ontario, L8S 4K1, Canada

  • Neonatal Intensive Care Unit - Mount Sinai Hospital

    ACTIVE_NOT_RECRUITING

    Toronto, Ontario, Canada

  • Newborn Health - IWK Health Centre

    ACTIVE_NOT_RECRUITING

    Halifax, Nova Scotia, Canada

  • Queen's University

    WITHDRAWN

    Kingston, Ontario, K7L 3N6, Canada

  • Royal Alexandra Hospital

    ACTIVE_NOT_RECRUITING

    Edmonton, Alberta, T5H 3V9, Canada

  • Sunnybrook Health Sciences Centre

    ACTIVE_NOT_RECRUITING

    Toronto, Ontario, Canada

  • University College Cork

    RECRUITING

    Cork, Ireland

  • Université de Sherbrooke

    RECRUITING

    Sherbrooke, Quebec, J1N 3C6, Canada

More trials for these conditions

Other studies related to the condition(s) this trial covers.