Can intense exercise boost heart recovery after bypass surgery?

NCT ID NCT07775742

This trial is taking on new participants right now.

First seen Aug 20, 2026 · Last updated Aug 21, 2026 · Updated 1 time

Summary

This trial tests whether high-intensity interval training (HIIT) or a home-based rehabilitation program can better improve exercise capacity in people who have had coronary artery bypass graft surgery. Participants, who are clinically stable and at low to moderate risk, will be assigned to one of the two programs. The main goal is to measure changes in peak metabolic equivalents (METs), a measure of how well the body uses oxygen during exercise, from the start to the end of the program.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
High-Intensity Interval Training (HIIT) program and a home-based cardiac rehabilitation program
What this could lead to
If effective, these exercise programs could become standard recommendations to help heart bypass patients regain fitness and improve daily function.
What could go wrong
The trial is relatively small and early, and results may not apply to all patients. Exercise carries a small risk of heart-related events, though participants are screened as low to moderate risk.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 84 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jul 2026

Expected to finish

Feb 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

55 to 58 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Participants will be eligible if they are clinically stable as defined by the American College of Cardiology/American Heart Association. 2. Only Participants will be stratified as low to moderate risk as identified by the American College of Sport Medicine/ 3. Mean age ± standard deviation, 55 ± 3 years. 4. All patients underwent coronary artery bypass graft surgery, rested at home for at least one month, and then returned to the center for a cardiac rehabilitation program Exclusion Criteria: 1. Patients will be excluded from this study if they had an ejection fraction of less than 40% at rest (high risk as defined by American Association of Cardiovascular and Pulmonary Rehabilitation Stratification). 2. Mental health disorders (such an anxiety or depression). 3. Any vision or hearing defects or any neurological, respiratory, or musculoskeletal conditions that have an impact on ambulation. 4. Irreversible heart failure. 5. Myocardial Infarction (MI) over the past month. 6. Persistent ventricular arrhythmias or unstable angina. 7. Any exercise restrictions.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Medina Cardiac Center

    RECRUITING

    Madinah, Saudi Arabia

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