Can combining two heart scans reveal more about clogged arteries?
NCT ID NCT05609214
The trial has finished. Results may not be published yet.
First seen Aug 21, 2026 · Last updated Aug 21, 2026
Summary
This observational study looks at whether combining PET and MRI heart scans gives doctors a fuller picture of blood flow and heart structure in people with known or suspected coronary artery disease. Researchers will compare the measurements from both imaging methods to see if they provide complementary information that could improve diagnosis. The study involves adults over 18 who have symptoms of possible coronary artery disease and are already scheduled for a stress CMR or PET exam.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- What this could lead to
- If successful, this could improve how doctors use heart imaging to diagnose and manage coronary artery disease, potentially leading to more accurate and personalized care.
- What could go wrong
- This is a small observational study, so its findings may not apply to everyone. It does not test a treatment, so it won't directly change patient outcomes.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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23 people
The number who actually took part.
- Started
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Nov 2022
- Finished
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Aug 2026
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Patients with known or suspected coronary artery disease who are referred for noninvasive cardiac evaluation, clinically indicated cardiac anatomy, viability and/or perfusion evaluation by MRI or PET scan
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Male and Female participants over the age of 18 years * Written informed consent by the participant after information about the research project * Symptoms consistent with possible coronary artery disease * Clinical referral for a vasodilator stress CMR and/or PET examination Exclusion Criteria: * Patients with high degree heart block * Contraindications to gadolinium-enhanced CMR examination * Severe claustrophobia * Specific implantable devices which are contraindicated for CMR * Current pregnancy * Advanced renal disease (GFR\<30) * Uncontrolled obstructive pulmonary disease or asthma * Atrial fibrillation at the time of study enrolment
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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University Hospital Zurich
Zurich, Switzerland
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