Could a higher oxytocin dose reduce C-Sections in obese women?
NCT ID NCT04760496
First seen Jan 06, 2026 · Last updated Jun 23, 2026 · Updated 25 times
Summary
This study tested whether giving a higher dose of oxytocin (a drug that strengthens contractions) could lower the rate of C-sections in obese women having their first baby. Over 400 women took part, receiving either a standard or a higher dose during labour. The goal was to see if the higher dose helps labour progress better and reduces the need for surgery.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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CHU d'Angers
Angers, France
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CHU de Bordeaux (Pellegrin)
Bordeaux, France
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CHU de Montpellier
Montpellier, France
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CHU de Nimes
Nîmes, France
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CHU de Poissy St Germain
Poissy, France
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CHU de Saint Etienne
Saint-Etienne, France
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CHU de Strasbourg (Centre Médico Chirurgical et Obstétrical)
Schiltigheim, France
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CHU de Strasbourg (Hôpital de Hautepierre)
Strasbourg, France
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Hôpital Bicêtre
Le Kremlin-Bicêtre, 94270, France
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Hôpital Béclère
Clamart, France
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Hôpital Cochin Port Royal
Paris, France
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Hôpital Tenon
Paris, France
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Oxytocin
What this could lead to
If successful, this could lead to a simple change in oxytocin dosing to reduce C-sections in obese women during labour.
What could go wrong
This is a completed Phase 4 trial, but results may not apply to all hospitals or populations. Higher oxytocin doses also carry risks like excessive contractions.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.