Could the 'Love Hormone' help teens lose weight?
NCT ID NCT04551482
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether oxytocin nasal spray can help teenagers with obesity manage their weight. Over 12 weeks, participants aged 10-18 will take the spray or a placebo four times daily. Researchers will measure changes in body mass index, body fat, and appetite to see if oxytocin offers a safe, effective way to control weight.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Oxytocin nasal spray
What this could lead to
If it works, this could point toward a new treatment option for obesity in teenagers that helps control appetite and body weight.
What could go wrong
This is an early Phase 2 trial with only 55 participants, so results may not apply to everyone. The treatment is short-term and may not lead to lasting weight loss.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Massachusetts General Hospital
RECRUITINGBoston, Massachusetts, 02114, United States
Contact Email: •••••@•••••