ER study tests higher buprenorphine dose to boost opioid treatment success

NCT ID NCT06494904

Recruiting now Disease control Sponsor: Yale University Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether a higher starting dose of buprenorphine in the emergency room helps more people with opioid use disorder engage in treatment within 10 days. It also looks at whether the higher dose reduces cravings, withdrawal symptoms, and use of illicit opioids. The trial enrolls 360 adults with moderate to severe opioid use disorder who are currently not in treatment.

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Conditions

The condition(s) this trial relates to.

opiate dependence

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

OPIOID-USE DISORDER

Contacts and locations

Locations

Cooper University Hospital
RECRUITING

Camden, New Jersey, 08103, United States
Highland Hospital
RECRUITING

Oakland, California, 94602, United States
Maine Medical Center
RECRUITING

Portland, Maine, 04102, United States
San Leandro Hospital
RECRUITING

San Leandro, California, 94578, United States
University of Utah Hospital
RECRUITING

Salt Lake City, Utah, 84132, United States

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