Can diet boost immunotherapy? study tests High-Fiber and fasting in melanoma

NCT ID NCT07680452

Recruiting now Knowledge-focused Sponsor: Charite University, Berlin, Germany Source: ClinicalTrials.gov ↗

First seen Jul 02, 2026 · Last updated Jul 30, 2026 · Updated 2 times

Summary

This study looks at whether adding a high-fiber diet and short-term fasting can help melanoma patients undergoing immunotherapy. Forty participants will follow a high-fiber diet, with half also doing 72-hour fasts during each treatment cycle, while 20 others serve as a control group. The main goal is to see if this approach is feasible, with exploratory checks on quality of life, side effects, and immune system changes.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: High-fiber diet and short-term fasting
What this could lead to: If successful, this could pave the way for larger studies on dietary support to improve immunotherapy effectiveness and reduce side effects in melanoma.
What could go wrong: This is an early feasibility study with only 60 participants, so results may not be conclusive. Dietary interventions can be hard to follow, and the study may not show clear benefits.

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Conditions

The condition(s) this trial relates to.

Fasting Intermittent Fasting melanoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

MELANOMA (SKIN CANCER)

Contacts and locations

Locations

Charité - Universitätsmedizin Berlin
RECRUITING

Berlin, State of Berlin, 10117, Germany

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