Could a high dose of steroids ease pain after lung surgery?
NCT ID NCT07213375
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether a high dose of the steroid dexamethasone can reduce pain when coughing after lung surgery (VATS lobectomy or segmentectomy) in patients who score high on a pain-expectation scale. 80 adults will be randomly assigned to receive either a high dose (1 mg/kg) or a low dose (8 mg) of dexamethasone during surgery. The main goal is to measure pain levels the morning after surgery.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Dexamethasone (a steroid drug)
What this could lead to
If it works, this could provide a better way to manage pain after lung surgery, reducing the need for strong painkillers.
What could go wrong
This is a small, early-phase trial (Phase 2/3) with only 80 participants. The high dose may not work better than the low dose, and steroids have side effects like high blood sugar or infection risk.
Disclaimer
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Department for Cardiothoracic Surgery, Rigshospitalet
RECRUITINGCopenhagen, Copenhagen, 2100, Denmark
Contact Phone: •••-•••-•••• Email: •••••@•••••