Could mountain air shape a Child's gut and immunity?
NCT ID NCT06157346
First seen Aug 18, 2026 · Last updated Aug 19, 2026 · Updated 1 time
Summary
This study looks at the gut bacteria of children aged 1 to 3 living at high altitudes in China's Diqing Tibetan Autonomous Prefecture. Researchers will collect stool samples to analyze the types of bacteria and their metabolites, comparing them with children from lower altitudes. The goal is to understand how altitude and diet influence gut flora, and how that might relate to growth and immune function. This is an observational study, so it does not test any treatment.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- This could reveal how high-altitude living shapes children's gut bacteria, potentially guiding ways to support growth and immune health in these communities.
- What could go wrong
- This is an observational study, so it can't prove cause and effect. Findings may not apply to other regions or altitudes.
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Study facts
What this study's own registry entry says, in plain language.
- Participants
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298 people
The number who actually took part.
- Started
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Oct 2023
- Finished
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Jul 2026
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
heathy children aged 1-3 years old
- Ages
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1 year to 3 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Children aged 1-3 years old * Both men and women; * The child's legal guardian signed the informed consent to participate in the study. * The legal guardian of the child commits to follow the study procedures and cooperate with the entire study process Exclusion Criteria: * Probiotics or antibiotics within 1 month * Associated with clinically significant abnormalities in liver and kidney function, nervous system, respiratory system, and coagulation function as determined by the investigator * Unstable vital signs; * Have other underlying medical conditions * Individuals deemed unsuitable for this clinical trial.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Ruijin Hospital, Shanghai Jiaotong University School of Medicine
Shanghai, Shanghai Municipality, 021, China
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