Surgery insight: how hernia repair affects the stomach valve

NCT ID NCT04450628

Ongoing Knowledge-focused Sponsor: Wake Forest University Health Sciences Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study looks at how hiatal hernia repair surgery changes the flexibility of the junction between the esophagus and stomach. Researchers will use a special balloon device during surgery to measure this flexibility in 25 adults. They hope to find links between these measurements and patients' later symptoms like heartburn or trouble swallowing.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: EndoFLIP device
What this could lead to: If successful, this could help surgeons tailor hiatal hernia repairs to improve patient outcomes like reflux and swallowing.
What could go wrong: This is a small, early-stage observational study with only 25 participants, so results may not apply broadly. The device is used during surgery and carries standard procedural risks.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

hiatus hernia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ESOPHAGOGASTRIC JUNCTION DISTENSIBILITY HIATAL HERNIA

Contacts and locations

Locations

Atrium Health - Carolinas Medical Center

Charlotte, North Carolina, 28203, United States

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