New drug combo targets Hard-to-Treat cancers in early trial

NCT ID NCT05238883

First seen Nov 21, 2025 · Last updated May 01, 2026 · Updated 18 times

Summary

This study tests an experimental drug called HFB200301, alone or with another drug (tislelizumab), in adults with advanced solid tumors like stomach, kidney, or lung cancer. The main goal is to find safe doses and check for side effects. About 72 people will take part, and the study is in two parts: first raising the dose to find a safe level, then testing that dose in specific cancer groups.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Hospital Clinico Universitario de Valencia

    Valencia, 46010, Spain

  • Hospital Universitario 12 de Octubre

    Madrid, 28041, Spain

  • Hospital Universitario Vall d'Hebron

    Barcelona, 08035, Spain

  • Mayo Clinic

    Scottsdale, Arizona, 85259, United States

  • Mayo Clinic

    Jacksonville, Florida, 32224, United States

  • Mayo Clinic

    Rochester, Minnesota, 55905, United States

  • NEXT Virginia Cancer Specialists

    Fairfax, Virginia, 22031, United States

  • The University of Texas, MD Anderson Cancer Center

    Houston, Texas, 77030, United States

  • USC/Norris Comprehensive Cancer Center

    Los Angeles, California, 90033, United States

  • Washington University School of Medicine

    St Louis, Missouri, 63110, United States

Conditions

Explore the condition pages connected to this study.