Houston program aims to keep opioid patients in care with medication and support

NCT ID NCT03396276

ENROLLING_BY_INVITATION Disease control Sponsor: The University of Texas Health Science Center, Houston Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a program called HEROES that combines medication (Suboxone), counseling, and community outreach to help people with opioid use disorder engage and stay in treatment. Researchers will enroll 3,000 participants in Houston to see if this approach improves treatment retention compared to standard care. The goal is to reduce opioid dependence through a supportive, multi-step system.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Suboxone (buprenorphine/naloxone)
What this could lead to: If successful, this could show that combining medication, counseling, and community outreach helps more people with opioid use disorder stay in treatment.
What could go wrong: This is a large Phase 4 trial, but results depend on real-world factors like patient motivation and follow-up. It may not work for everyone, and Suboxone can cause side effects like nausea or withdrawal symptoms.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

opiate dependence

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

OPIOID-USE DISORDER

Contacts and locations

Locations

The University of Texas Health Science Center at Houston

Houston, Texas, 77030, United States

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Other studies related to the condition(s) this trial covers.