Botox or gas? new trial tests best prep for big hernia surgery
NCT ID NCT07549113
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study compares four ways to prepare patients with large incisional hernias before surgery: Botox injections, gradual air inflation in the belly (pneumoperitoneum), both combined, or standard care. The goal is to see which approach helps surgeons close the hernia more safely and with fewer complications. About 120 adults will take part.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Botulinum toxin A (Botox)
What this could lead to
If successful, this could identify the best pre-surgery preparation to make hernia repair safer and reduce complications.
What could go wrong
This is a relatively small, early-stage comparative study, so results may not apply to all patients. The interventions also carry risks like infection or muscle weakness.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Ochapovsky Regional Clinical Hospital No.1
RECRUITINGKrasnodar, Krasnodarskiy Kray, 350000, Russia
Contact Phone: •••-•••-•••• Email: •••••@•••••