Ancient herbs face off against metformin in diabetes trial
NCT ID NCT07279909
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This phase 3 trial tests a capsule made from four traditional anti-diabetic herbs (Syzygium cumini, bitter melon, Wrightia tinctoria, and Gymnema sylvestre) in 500 adults with type 2 diabetes. Participants take either the herbal capsule or the standard drug metformin three times daily for six months. The study aims to see if the herbal blend can lower blood sugar and HbA1c as effectively as metformin, while also checking safety.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Polyherbal capsule (Syzygium cumini, bitter melon, Wrightia tinctoria, Gymnema sylvestre)
- What this could lead to
- If it works, this could offer a natural, plant-based option to help control blood sugar in type 2 diabetes, possibly as an alternative or add-on to standard drugs like metformin.
- What could go wrong
- This is a single trial with 500 people, and results may not apply to everyone. Herbal products can vary in potency, and the combination hasn't been tested before, so safety and effectiveness are still unproven.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for ABILITY OF EXPERIMENTAL DRUG TO LOWER HBA1C COMPARE TO METFORMIN are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Mehboob Faryal Diagnostic Center
Karachi, Sindh, 74700, Pakistan
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Your genes may decide if metformin works for you
- Could a Low-Calorie diet and Weight-Loss drug send type 2 diabetes into remission?
- Could immune cells in fat hold the key to Obesity-Related diseases?
- Your DNA may determine if Weight-Loss drugs work — a trial hunts for clues
- Can a smartphone app and wearable help tame type 2 diabetes?
- Can a smartphone app help teens tame type 1 diabetes?