Ancient herbs face off against metformin in diabetes trial
NCT ID NCT07279909
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This phase 3 trial tests a capsule made from four traditional anti-diabetic herbs (Syzygium cumini, bitter melon, Wrightia tinctoria, and Gymnema sylvestre) in 500 adults with type 2 diabetes. Participants take either the herbal capsule or the standard drug metformin three times daily for six months. The study aims to see if the herbal blend can lower blood sugar and HbA1c as effectively as metformin, while also checking safety.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Polyherbal capsule (Syzygium cumini, bitter melon, Wrightia tinctoria, Gymnema sylvestre)
What this could lead to
If it works, this could offer a natural, plant-based option to help control blood sugar in type 2 diabetes, possibly as an alternative or add-on to standard drugs like metformin.
What could go wrong
This is a single trial with 500 people, and results may not apply to everyone. Herbal products can vary in potency, and the combination hasn't been tested before, so safety and effectiveness are still unproven.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Mehboob Faryal Diagnostic Center
Karachi, Sindh, 74700, Pakistan