Blood filter aims to calm deadly inflammation in septic shock
NCT ID NCT07715110
First seen Jul 20, 2026 · Last updated Jul 21, 2026 · Updated 1 time
Summary
This pilot trial tests whether a special cartridge placed in a blood-filtering machine can improve outcomes for people with septic shock, a severe and often deadly infection response. The cartridge is designed to remove inflammatory molecules from the blood, which may reduce organ damage and help patients recover. The study includes two groups: those with standard septic shock and those with a more severe form called refractory septic shock. Researchers will compare a combination of survival and early improvements in inflammation, organ function, and blood pressure.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- A resin-based hemoadsorption cartridge inserted into a continuous renal replacement therapy circuit to filter inflammatory mediators from the blood.
- What this could lead to
- If successful, this approach could provide a new way to reduce inflammation and organ damage in septic shock, potentially lowering the high death rate.
- What could go wrong
- This is a very small pilot study with only 16 participants, so results may not apply broadly. The treatment is experimental and may not improve outcomes or could cause complications.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Ervigio Corral-Torres
Madrid, Es-Md, 28040, Spain
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Hospital Clínico San Carlos
Madrid, Es-Md, 28040, Spain
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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