Warm oxygen may shield patients from Post-Surgery breathing danger

NCT ID NCT07778420

Not yet recruiting Disease control Sponsor: Second Affiliated Hospital of Xi'an Jiaotong University Source: ClinicalTrials.gov ↗

First seen Aug 21, 2026 · Last updated Aug 21, 2026

Summary

This trial tests whether giving heated and humidified oxygen during recovery from general anesthesia can reduce the chance of early hypoxemia—a dangerous drop in blood oxygen levels—compared to standard room-temperature oxygen. About 2,000 adults undergoing surgery will be randomly assigned to receive one of the two oxygen types through a face mask. The main goal is to see if the heated version lowers the rate of hypoxemia within the first 10 minutes of recovery, which could lead to safer post-surgery care.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Heated and humidified oxygen therapy delivered via face mask
What this could lead to: If effective, this simple oxygen delivery method could become a standard practice to prevent dangerous drops in blood oxygen levels after surgery, improving patient safety and recovery.
What could go wrong: This is an early-stage trial, and the benefit may be small or not apply to all patients. There is also a risk of nasal discomfort or other minor side effects from the heated oxygen.

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Conditions

The condition(s) this trial relates to.

Hypoxia Postoperative Complications

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ANESTHESIA RECOVERY PERIOD HYPOXEMIA POSTOPERATIVE COMPLICATIONS

Contacts and locations

Locations

General Hospital of Western Theater Command, PLA

Chengdu, Sichuan, 610083, China
Luoyang Central Hospital

Luoyang, Henan, 471009, China
Shaanxi Nuclear Industry 215 Hospital

Xianyang, Shaanxi, 712000, China
Shaanxi Provincial People's Hospital

Xi'an, Shaanxi, 710068, China
Sichuan Cancer Hospital

Chengdu, Sichuan, 610041, China
The Second Affiliated Hospital of Xi'an Jiaotong University

Xi'an, Shaanxi, 710004, China
Xi'an Central Hospital

Xi'an, Shaanxi, 710003, China
Xi'an People's Hospital

Xi'an, Shaanxi, 710004, China

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