Heart pump vs. meds: major trial aims to extend lives in advanced heart failure

NCT ID NCT06526195

Summary

This trial is testing if implanting a mechanical heart pump (HeartMate 3) early can help people with advanced heart failure live longer and have a better quality of life compared to staying on strong medications alone. It will enroll about 850 adults whose heart failure is worsening despite taking the best available drugs. The study uses a special sensor to monitor lung pressure, helping doctors decide who might benefit most from getting the pump.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • A.O.U. Citta della Salute e della Scienza di Torino

    RECRUITING

    Turin, Piedmont, 10126, Italy

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • AKH -Wien

    RECRUITING

    Vienna, Vienna, 1090, Austria

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Abington Memorial Hospital

    RECRUITING

    Abington, Pennsylvania, 19001, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Advocate Health & Hospitals Corporation

    RECRUITING

    Oakbrook Terrace, Illinois, 60181, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Allegheny General Hospital

    RECRUITING

    Pittsburgh, Pennsylvania, 15212, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Ascension Texas Cardiovascular

    RECRUITING

    Austin, Texas, 78705, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Aurora Medical Group

    RECRUITING

    Milwaukee, Wisconsin, 53215, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Banner-University Medical Center Phoenix

    RECRUITING

    Phoenix, Arizona, 85006, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Baptist Health Medical Center

    RECRUITING

    Little Rock, Arkansas, 72205, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Baylor University Hospital

    RECRUITING

    Dallas, Texas, 75246, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • CHI St. Luke's Health Baylor College of Medicine Medical Center

    RECRUITING

    Houston, Texas, 77030, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Carolinas Medical Center

    RECRUITING

    Charlotte, North Carolina, 28203, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Christ Hospital

    RECRUITING

    Cincinnati, Ohio, 45219, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Cleveland Clinic Florida

    RECRUITING

    Weston, Florida, 33331, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Deutsches Herzzentrum der Charité

    RECRUITING

    Berlin, State of Berlin, 13353, Germany

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Erasmus MC - Thoraxcenter

    RECRUITING

    Rotterdam, Holland, 3015 CE, Netherlands

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Hackensack University Medical Center

    RECRUITING

    Hackensack, New Jersey, 07601, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Henry Ford Hospital

    RECRUITING

    Detroit, Michigan, 48202, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Herzzentrum Leipzig GmbH

    RECRUITING

    Leipzig, Saxony, 04289, Germany

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Houston Methodist

    RECRUITING

    Houston, Texas, 77030, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • IKEM Prague

    RECRUITING

    Prague, CBohmia, 14021, Czechia

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Integris Baptist Medical Center

    RECRUITING

    Oklahoma City, Oklahoma, 73112, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Kansas University Medical Center

    RECRUITING

    Kansas City, Kansas, 66160, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • King Fahad Medical City

    RECRUITING

    Riyadh, Riyadh Region, 11525, Saudi Arabia

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • King Faisal Specialist Hospital

    RECRUITING

    Riyadh, Riyadh Region, 12713, Saudi Arabia

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Massachusetts General Hospital

    RECRUITING

    Boston, Massachusetts, 02114, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Mayo Clinic

    RECRUITING

    Rochester, Minnesota, 55905, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Medical University of South Carolina

    RECRUITING

    Charleston, South Carolina, 29425, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Medizinische Hochschule Hannover

    RECRUITING

    Hanover, Saxon, 30625, Germany

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Minneapolis Heart Institute

    RECRUITING

    Minneapolis, Minnesota, 55407, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Montefiore Medical Center - Moses Campus

    RECRUITING

    The Bronx, New York, 10467, United States

    Contact Email: •••••@•••••

    Contact

  • New York-Presbyterian/Columbia University Medical Center

    RECRUITING

    New York, New York, 10032, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Newark Beth Israel Medical Center

    RECRUITING

    Newark, New Jersey, 07112, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • North Shore University Hospital

    RECRUITING

    Manhasset, New York, 11030, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Norton Hospital

    RECRUITING

    Louisville, Kentucky, 40202, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Oklahoma Heart Institute at Utica

    RECRUITING

    Tulsa, Oklahoma, 74104, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Oregon Health & Science University

    RECRUITING

    Portland, Oregon, 97239, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Penn State Milton S. Hershey Medical Center

    RECRUITING

    Hershey, Pennsylvania, 17033, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Piedmont Augusta Hospital

    RECRUITING

    Augusta, Georgia, 30901, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Piedmont Heart Institute

    RECRUITING

    Atlanta, Georgia, 30309, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Prisma Health Midlands

    RECRUITING

    Columbia, South Carolina, 29203, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Rigshospitalet

    RECRUITING

    Copenhagen, Copenhagen, 2100, Denmark

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Saint Francis Hospital

    RECRUITING

    Tulsa, Oklahoma, 74136, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Scott & White Memorial Hospital

    RECRUITING

    Temple, Texas, 76508, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Shands at the University of Florida

    RECRUITING

    Gainesville, Florida, 32610, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Spectrum Health Butterworth Hospital

    RECRUITING

    Grand Rapids, Michigan, 49503, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • St. Luke's Hospital

    RECRUITING

    Kansas City, Missouri, 64111, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • St. Vincent Hospital

    RECRUITING

    Indianapolis, Indiana, 46240, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Sutter Medical Center

    RECRUITING

    Sacramento, California, 95816, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • The Cleveland Clinic Foundation

    RECRUITING

    Cleveland, Ohio, 44195, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • The Heart Hospital Baylor Plano

    RECRUITING

    Plano, Texas, 75093, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The Stern Cardiovascular Foundation

    RECRUITING

    Memphis, Tennessee, 38120, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • UMC Utrecht

    RECRUITING

    Utrecht, Utrecht, 3584 CX, Netherlands

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • UTHealth Memorial Hermann

    RECRUITING

    Houston, Texas, 77030, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • University of California at San Francisco

    RECRUITING

    San Francisco, California, 94143, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of Iowa Hospitals & Clinics

    RECRUITING

    Iowa City, Iowa, 52242, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of Kentucky

    RECRUITING

    Lexington, Kentucky, 40536, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • University of Nebraska Medical Center

    RECRUITING

    Omaha, Nebraska, 68198, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of North Carolina at Chapel Hill

    RECRUITING

    Chapel Hill, North Carolina, 27599, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • University of Rochester Medical Center

    RECRUITING

    Rochester, New York, 14642, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of Utah Hospital

    RECRUITING

    Salt Lake City, Utah, 84132, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Washington Hospital Center

    RECRUITING

    Washington D.C., District of Columbia, 20010, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • WellStar Kennestone Hospital

    RECRUITING

    Marietta, Georgia, 30060, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.