Heart failure emergency: which drug works best first?

NCT ID NCT05276219

Recruiting now Disease control Sponsor: Rigshospitalet, Denmark Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether opening blood vessels (vasodilation) or removing fluid (diuretics) is better for treating sudden fluid buildup in the lungs from heart failure. About 1,100 adults with severe shortness of breath and low oxygen levels will receive one of three treatments in the emergency room. The goal is to see which approach keeps patients alive and out of the hospital longer over 30 days.

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Conditions

The condition(s) this trial relates to.

congestive heart failure heart failure pulmonary edema

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ACUTE HEART FAILURE CONGESTIVE HEART FAILURE PULMONARY EDEMA

Contacts and locations

Locations

Bispebjerg Hospital
RECRUITING

Copenhagen, Copenhagen, 2000, Denmark
Hvidovre Hospital
RECRUITING

Copenhagen, Copenhagen, 2650, Denmark
Nordsjællands Hospital
RECRUITING

Hillerød, Denmark
Roskilde Hospital
NOT_YET_RECRUITING

Roskilde, Denmark

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