Heart failure and AF: new clues from inflammation and genes?

NCT ID NCT07152301

Completed Knowledge-focused Sponsor: University of Palermo Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This completed study enrolled 164 adults with chronic heart failure, some also with permanent atrial fibrillation. Researchers measured blood markers of inflammation and certain microRNAs (genetic molecules) and used echocardiograms to look at heart structure. The goal was to understand how inflammation and genetics relate to heart remodeling in these patients.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this could help identify new markers or targets for better managing heart failure and atrial fibrillation together.
What could go wrong: This is an observational study, not a treatment trial. It cannot prove cause and effect, and results may not lead to direct patient benefits.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

atrial fibrillation congestive heart failure

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ATRIAL FIBRILLATION (PERMANENT) CONGESTIVE HEART FAILURE CHRONIC

Contacts and locations

Locations

Internal Medicine and Stroke Care Ward, Policlinic Hospital of Palermo, Sicily

Palermo, PA, 90127, Italy

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