New hope in ALS fight: DNL343 drug tested in major trial
NCT ID NCT05842941
First seen Jan 29, 2026 · Last updated May 13, 2026 · Updated 16 times
Summary
This clinical trial tested a drug called DNL343 in 249 people with ALS, a disease that weakens muscles over time. The goal was to see if DNL343 could slow the disease's progress and improve survival. The study used a flexible platform design to test multiple treatments efficiently.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Healey Center for ALS at Massachusetts General Hospital
Boston, Massachusetts, 02114, United States
Conditions
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