Major ALS trial tests multiple drugs simultaneously in race against time

NCT ID NCT04297683

Recruiting now Disease control Sponsor: Merit E. Cudkowicz, MD Source: ClinicalTrials.gov ↗

Summary

This large, ongoing trial is testing several experimental drugs at the same time to find treatments that can slow the progression of ALS (Lou Gehrig's disease) and help people live longer. The study will enroll 1,500 adults recently diagnosed with ALS who can still swallow pills. Participants are randomly assigned to receive either an experimental drug or a placebo, with new treatments being added to the trial as they become available.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

Atrium Health
RECRUITING

Charlotte, North Carolina, 28207, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••

Contact Email: •••••@•••••
Augusta University
ACTIVE_NOT_RECRUITING

Augusta, Georgia, 30912, United States
Barrow Neurological Institute
ACTIVE_NOT_RECRUITING

Phoenix, Arizona, 85013, United States
Beth Israel Deaconess Medical Center
RECRUITING

Boston, Massachusetts, 02215, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
Cedars-Sinai Medical Center
ACTIVE_NOT_RECRUITING

Los Angeles, California, 90048, United States
Cleveland Clinic
RECRUITING

Cleveland, Ohio, 44195, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
Columbia University
ACTIVE_NOT_RECRUITING

New York, New York, 10032, United States
Dartmouth-Hitchcock Medical Center
ACTIVE_NOT_RECRUITING

Lebanon, New Hampshire, 03756, United States
Dent Neurologic Institute
ACTIVE_NOT_RECRUITING

Amherst, New York, 14226, United States
Duke University
ACTIVE_NOT_RECRUITING

Durham, North Carolina, 27702, United States
Essentia Health
RECRUITING

Duluth, Minnesota, 55805, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
Forbes Norris MDA/ALS Research Center, California Pacific Medical Center
RECRUITING

San Francisco, California, 94115, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
George Washington University
ACTIVE_NOT_RECRUITING

Washington D.C., District of Columbia, 20037, United States
Georgetown University
RECRUITING

Washington D.C., District of Columbia, 20007, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
Hackensack University Medical Center
ACTIVE_NOT_RECRUITING

Hackensack, New Jersey, 07601, United States
Henry Ford Health System
RECRUITING

Detroit, Michigan, 48202, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
Hospital for Special Care
RECRUITING

New Britain, Connecticut, 06053, United States

Contact Email: •••••@•••••
Houston Methodist
ACTIVE_NOT_RECRUITING

Houston, Texas, 77030, United States
Indiana University Health
ACTIVE_NOT_RECRUITING

Indianapolis, Indiana, 46202, United States
Jefferson Weinberg ALS Center, Thomas Jefferson University
RECRUITING

Philadelphia, Pennsylvania, 19107, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
Johns Hopkins University
ACTIVE_NOT_RECRUITING

Baltimore, Maryland, 21205, United States
Kaiser Permanente Los Angeles Medical Center
ACTIVE_NOT_RECRUITING

Los Angeles, California, 90027, United States
Lehigh Valley Health Network
ACTIVE_NOT_RECRUITING

Allentown, Pennsylvania, 18103, United States
Lewis Katz School of Medicine at Temple University
ACTIVE_NOT_RECRUITING

Philadelphia, Pennsylvania, 19140, United States
Loma Linda University Health
ACTIVE_NOT_RECRUITING

Loma Linda, California, 92354, United States
Massachusetts General Hospital
RECRUITING

Boston, Massachusetts, 02114, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
Mayo Clinic - Rochester
ACTIVE_NOT_RECRUITING

Rochester, Minnesota, 55902, United States
Mayo Clinic Florida
ACTIVE_NOT_RECRUITING

Jacksonville, Florida, 32224, United States
Mayo Clinic Scottsdale
RECRUITING

Scottsdale, Arizona, 85259, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
Medical College of Wisconsin
ACTIVE_NOT_RECRUITING

Milwaukee, Wisconsin, 53226, United States
Neurology Associates, P.C./Somnos Clinical Research
ACTIVE_NOT_RECRUITING

Lincoln, Nebraska, 68506, United States
Northwestern University
ACTIVE_NOT_RECRUITING

Chicago, Illinois, 60611, United States
Nova Southeastern University
RECRUITING

Davie, Florida, 33024, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
Ochsner Health System
ACTIVE_NOT_RECRUITING

New Orleans, Louisiana, 70115, United States
Penn State Hershey
ACTIVE_NOT_RECRUITING

Hershey, Pennsylvania, 17033, United States
Providence Brain and Spine Institute ALS Center
ACTIVE_NOT_RECRUITING

Portland, Oregon, 97213, United States
SUNY Upstate
ACTIVE_NOT_RECRUITING

Syracuse, New York, 13202, United States
Saint Alphonsus Regional Medical Center
ACTIVE_NOT_RECRUITING

Boise, Idaho, 83704, United States
Saint Louis University
ACTIVE_NOT_RECRUITING

St Louis, Missouri, 63104, United States
Spectrum Health/Corewell Health
ACTIVE_NOT_RECRUITING

Grand Rapids, Michigan, 49525, United States
Stony Brook University Hospital
ACTIVE_NOT_RECRUITING

Stony Brook, New York, 11794, United States
Swedish Medical Center
ACTIVE_NOT_RECRUITING

Seattle, Washington, 98122, United States
Texas Neurology
RECRUITING

Dallas, Texas, 75214, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
The Ohio State University
ACTIVE_NOT_RECRUITING

Columbus, Ohio, 43221, United States
UTHSCSA
ACTIVE_NOT_RECRUITING

San Antonio, Texas, 78229, United States
University of Arkansas for Medical Sciences
ACTIVE_NOT_RECRUITING

Little Rock, Arkansas, 72205, United States
University of California, Irvine
ACTIVE_NOT_RECRUITING

Orange, California, 92868, United States
University of California, San Francisco
ACTIVE_NOT_RECRUITING

San Francisco, California, 94143, United States
University of Chicago
ACTIVE_NOT_RECRUITING

Chicago, Illinois, 60637, United States
University of Cincinnati
RECRUITING

Cincinnati, Ohio, 45219, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
University of Colorado
ACTIVE_NOT_RECRUITING

Aurora, Colorado, 80045, United States
University of Florida
ACTIVE_NOT_RECRUITING

Gainesville, Florida, 32610, United States
University of Iowa Hospitals and Clinics
RECRUITING

Iowa City, Iowa, 52242, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
University of Kansas Medical Center
RECRUITING

Fairway, Kansas, 66205, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
University of Kentucky
ACTIVE_NOT_RECRUITING

Lexington, Kentucky, 40536, United States
University of Massachusetts Medical School
RECRUITING

North Worcester, Massachusetts, 01655, United States

Contact Email: •••••@•••••

Contact Email: •••••@•••••
University of Miami
ACTIVE_NOT_RECRUITING

Miami, Florida, 33136, United States
University of Michigan
RECRUITING

Ann Arbor, Michigan, 48109, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
University of Minnesota Medical School
ACTIVE_NOT_RECRUITING

Minneapolis, Minnesota, 55455, United States
University of Missouri Health Care
NOT_YET_RECRUITING

Columbia, Missouri, 65212, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
University of Nebraska Medical Center
RECRUITING

Omaha, Nebraska, 68198, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
University of North Carolina
ACTIVE_NOT_RECRUITING

Chapel Hill, North Carolina, 27599, United States
University of Penn
ACTIVE_NOT_RECRUITING

Philadelphia, Pennsylvania, 19107, United States
University of Pittsburg Medical Center
RECRUITING

Pittsburgh, Pennsylvania, 15232, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
University of South Florida
ACTIVE_NOT_RECRUITING

Tampa, Florida, 33612, United States
University of Southern California
RECRUITING

Los Angeles, California, 90033, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
University of Utah
ACTIVE_NOT_RECRUITING

Salt Lake City, Utah, 84132, United States
University of Virginia
ACTIVE_NOT_RECRUITING

Charlottesville, Virginia, 22908, United States
University of Washington
ACTIVE_NOT_RECRUITING

Seattle, Washington, 98195, United States
Vanderbilt University Medical Center
RECRUITING

Nashville, Tennessee, 37232, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
Virginia Commonwealth University
ACTIVE_NOT_RECRUITING

Henrico, Virginia, 23233, United States
Wake Forest Health Science
RECRUITING

Winston-Salem, North Carolina, 27157, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
Washington University School of Medicine
RECRUITING

St Louis, Missouri, 63110, United States

Contact Email: •••••@•••••
Yale University
ACTIVE_NOT_RECRUITING

New Haven, Connecticut, 06519, United States

Conditions

Explore the condition pages connected to this study.

AMYOTROPHIC LATERAL SCLEROSIS