New cancer combo aims to spare patients harsh radiation

NCT ID NCT03174275

Summary

This study is testing a three-step treatment for people with advanced head and neck cancer that can be removed by surgery. First, patients receive a combination of three drugs (carboplatin, nab-paclitaxel, and durvalumab) to try to shrink the cancer. Then, they have surgery. Finally, they receive additional therapy tailored to their specific risk level after surgery, with the goal of avoiding standard radiation treatment and its difficult side effects.

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Contacts and locations

Locations

  • Lineberger Comprehensive Cancer Center at University of North Carolina Chapel Hill

    Chapel Hill, North Carolina, 27599, United States

  • Vanderbilt University Medical Center

    Nashville, Tennessee, 37232, United States

Conditions

Explore the condition pages connected to this study.