New radiation cocktail aims to cut prostate cancer treatment time

NCT ID NCT01655836

First seen Jun 26, 2026 ยท Last updated Jun 26, 2026

Summary

This phase 1 trial tests a combination of two radiation techniques for men with intermediate risk prostate cancer. First, a high dose of radiation is placed inside the prostate for 10-20 minutes (brachytherapy), followed by three weeks of highly targeted external radiation (SBRT). The goal is to see if this shorter treatment plan is safe and tolerable. 42 men are enrolled.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
radiation therapy (high dose rate brachytherapy and stereotactic body radiation therapy)
What this could lead to
If successful, this could lead to a shorter, more precise radiation treatment option for intermediate risk prostate cancer with fewer side effects.
What could go wrong
This is an early phase 1 trial with only 42 participants, focused on safety. It may not show better outcomes than standard treatments, and there are risks of radiation-related side effects.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Thomas Jefferson University

    Philadelphia, Pennsylvania, 19107, United States

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Other studies related to the condition(s) this trial covers.