Could a blood pressure drug combo tame panic attacks?

NCT ID NCT06483789

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This phase 2 trial tests a new drug called HB-1, which combines two blood pressure medicines (telmisartan and verapamil), to see if it can reduce unexpected panic attacks in people with panic disorder. The study plans to enroll 240 adults aged 18 to 65 and compare HB-1 against placebo and each drug alone. However, the trial is currently suspended, so results are on hold.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

HB-1 (a combination of telmisartan and verapamil)

What this could lead to

If it works, this could offer a new treatment option for people with panic disorder, potentially reducing unexpected panic attacks.

What could go wrong

This is an early phase 2 trial that is currently suspended, so results are uncertain. The drug may not work better than placebo or existing treatments, and side effects are possible.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

panic disorder psychiatric disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Canopy Clinical Sutherland

    Miranda, New South Wales, 2228, Australia

  • Canopy Clinical Wollongong

    Wollongong, New South Wales, 2500, Australia

  • Clinical Trials Institute

    Torquay, Victoria, 3228, Australia

  • Clinitrials

    West Perth, Western Australia, 6005, Australia

  • East Sydney Doctors

    Darlinghurst, New South Wales, 2010, Australia

  • Innovate Clinical Research

    Waitara, New South Wales, 2077, Australia

  • Mackay Hospital and Health Service

    Mackay, Queensland, 4740, Australia

  • Momentum Clinical Research Darlinghurst

    Darlinghurst, New South Wales, 2010, Australia

  • Multidisciplinary Alfred Psychiatry Research Clinic

    Melbourne, Victoria, 3004, Australia

  • NeuroCentrix

    Carlton, Victoria, 3053, Australia

  • Novatrials

    Charlestown, New South Wales, 2290, Australia

  • Paratus Clinical Research Brisbane

    Herston, Queensland, 4006, Australia

  • Paratus Clinical Research Canberra

    Canberra, Australian Capital Territory, 2617, Australia

  • Paratus Clinical Research Melbourne

    Northcote, Victoria, 3070, Australia

  • Paratus Clinical Research Western Sydney

    Blacktown, New South Wales, 2148, Australia

  • Peninsula Therapeutic and Research Group

    Frankston, Victoria, 3199, Australia

  • Ramsay Clinic Albert Road

    Melbourne, Victoria, 3004, Australia

  • South Australian Health and Medical Research Institute

    Adelaide, South Australia, 5000, Australia

  • Westmead Hospital

    Westmead, New South Wales, 2145, Australia