Could a blood pressure drug combo tame panic attacks?

NCT ID NCT06483789

Terminated Disease control Sponsor: HB BioTech, LLC Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This phase 2 trial tests a new drug called HB-1, which combines two blood pressure medicines (telmisartan and verapamil), to see if it can reduce unexpected panic attacks in people with panic disorder. The study plans to enroll 240 adults aged 18 to 65 and compare HB-1 against placebo and each drug alone. However, the trial is currently suspended, so results are on hold.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: HB-1 (a combination of telmisartan and verapamil)
What this could lead to: If it works, this could offer a new treatment option for people with panic disorder, potentially reducing unexpected panic attacks.
What could go wrong: This is an early phase 2 trial that is currently suspended, so results are uncertain. The drug may not work better than placebo or existing treatments, and side effects are possible.

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Conditions

The condition(s) this trial relates to.

panic disorder psychiatric disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

MENTAL ILLNESS PANIC DISORDER

Contacts and locations

Locations

Canopy Clinical Sutherland

Miranda, New South Wales, 2228, Australia
Canopy Clinical Wollongong

Wollongong, New South Wales, 2500, Australia
Clinical Trials Institute

Torquay, Victoria, 3228, Australia
Clinitrials

West Perth, Western Australia, 6005, Australia
East Sydney Doctors

Darlinghurst, New South Wales, 2010, Australia
Innovate Clinical Research

Waitara, New South Wales, 2077, Australia
Mackay Hospital and Health Service

Mackay, Queensland, 4740, Australia
Momentum Clinical Research Darlinghurst

Darlinghurst, New South Wales, 2010, Australia
Multidisciplinary Alfred Psychiatry Research Clinic

Melbourne, Victoria, 3004, Australia
NeuroCentrix

Carlton, Victoria, 3053, Australia
Novatrials

Charlestown, New South Wales, 2290, Australia
Paratus Clinical Research Brisbane

Herston, Queensland, 4006, Australia
Paratus Clinical Research Canberra

Canberra, Australian Capital Territory, 2617, Australia
Paratus Clinical Research Melbourne

Northcote, Victoria, 3070, Australia
Paratus Clinical Research Western Sydney

Blacktown, New South Wales, 2148, Australia
Peninsula Therapeutic and Research Group

Frankston, Victoria, 3199, Australia
Ramsay Clinic Albert Road

Melbourne, Victoria, 3004, Australia
South Australian Health and Medical Research Institute

Adelaide, South Australia, 5000, Australia
Westmead Hospital

Westmead, New South Wales, 2145, Australia

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